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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPK2
All Species:
5.45
Human Site:
S490
Identified Species:
15
UniProt:
Q86TB3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86TB3
NP_443179.3
2170
237013
S490
N
L
L
N
M
D
E
S
V
R
E
T
E
M
K
Chimpanzee
Pan troglodytes
XP_523937
2152
234020
S490
N
L
L
N
M
D
E
S
V
R
E
T
E
M
K
Rhesus Macaque
Macaca mulatta
XP_001089001
1927
209300
A343
G
D
A
G
P
M
V
A
T
A
G
F
C
G
H
Dog
Lupus familis
XP_541086
2143
231365
A518
N
L
L
N
M
D
K
A
V
I
E
T
A
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZB0
1921
208932
G337
P
T
R
Q
P
L
P
G
S
Y
G
Q
E
P
T
Rat
Rattus norvegicus
XP_574162
1448
157347
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510874
2304
253497
Q642
P
P
N
M
N
S
M
Q
A
K
P
S
P
R
G
Chicken
Gallus gallus
XP_424461
1802
200116
R218
K
F
K
G
V
N
V
R
R
D
P
S
T
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688314
1984
219144
S400
V
V
D
Q
Y
V
F
S
E
N
I
G
Q
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
78
61.9
N.A.
51
36.4
N.A.
34.3
30
N.A.
22.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.4
80.9
71.9
N.A.
61
47.5
N.A.
47.8
46.3
N.A.
40.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
6.6
0
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
86.6
N.A.
6.6
0
N.A.
13.3
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
23
12
12
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
12
12
0
0
34
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
23
0
12
0
34
0
34
12
0
% E
% Phe:
0
12
0
0
0
0
12
0
0
0
0
12
0
0
0
% F
% Gly:
12
0
0
23
0
0
0
12
0
0
23
12
0
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% I
% Lys:
12
0
12
0
0
0
12
0
0
12
0
0
0
0
34
% K
% Leu:
0
34
34
0
0
12
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
34
12
12
0
0
0
0
0
0
34
0
% M
% Asn:
34
0
12
34
12
12
0
0
0
12
0
0
0
0
0
% N
% Pro:
23
12
0
0
23
0
12
0
0
0
23
0
12
12
0
% P
% Gln:
0
0
0
23
0
0
0
12
0
0
0
12
12
0
0
% Q
% Arg:
0
0
12
0
0
0
0
12
12
23
0
0
0
12
0
% R
% Ser:
0
0
0
0
0
12
0
34
12
0
0
23
0
0
12
% S
% Thr:
0
12
0
0
0
0
0
0
12
0
0
34
12
0
12
% T
% Val:
12
12
0
0
12
12
23
0
34
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
12
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _